Nano Synthesis and Characterization of Complex Derived from Silver Metal Conjugated with Midodrine Hydrochloride

The stability constant Kf for the complexation of Ag(Ⅰ) metal ion with Midodrine hydrochloride were determinedby spectrophotometric method at room temperature .The colored complexes measured 300 nm. found to be 5.47 by mole ratio method. stoichiometry formed between drug and Ag (Ⅰ) are 1:1 M/L ratio. Silver conjugated Nano synthesized characterized UV/Visible spectroscopy, SEM, XRD FT-IR. spectra –Ag nanoparticle in range 322 conformThe crystallite size - nanoparticles 64.5 nmfrom Debye Scherer formula.Thecrystallinity is Face centered cubic structure. SEM conform particle surface morphology, FTIR analyzed involvement -NH2 group stabilized silver nanoparticle. This research focuses on complexation, synthesis characterization Drug-silver antihypotention therapy.